janulet

janulet

Local anesthetics are widely used in many specialized surgeries, including cosmetic procedures. Since the injection of anesthetics is painful, it can increase the patient’s anxiety. Moreover, these compounds may cause tissue edema and damage at the lesion site; therefore, the use of local anesthetics depends on the treatment area and the patient’s pain tolerance threshold.

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Introducing janulet

Local anesthetics are widely used in many specialized surgeries, including cosmetic procedures. Since the injection of anesthetics is painful, it can increase the patient’s anxiety. Moreover, these compounds may cause tissue edema and damage at the lesion site; therefore, the use of local anesthetics depends on the treatment area and the patient’s pain tolerance threshold. The combination of lidocaine, epinephrine, and tetracaine (LET), marketed under the brand name JanuLET, is suitable for medical procedures such as tattooing, micropigmentation, hair transplantation, and microneedling due to its rapid onset of anesthesia, long-lasting effect, and ability to reduce swelling and bleeding in the treated area. The micropigmentation technique, also known as medical tattooing, is used to treat skin conditions such as vitiligo, burn scars, hypertrophic scars, pigmented skin lesions, areola reconstruction, and other defects caused by accidents or surgery. In this method, pigment granules are implanted beneath the epidermal layer of the skin (with minimal tissue damage) using a specialized device, restoring the natural tone and appearance of the patient’s skin. The technique and skill of the specialist physician in preparing the appropriate pigment and predicting the outcome of the procedure are of great importance. Another application of JanuLET is in microneedling, performed with a micropigmentation device (without pigment). In this procedure, tiny micro-channels are created in the skin, stimulating its natural regenerative ability and promoting the production of large amounts of collagen and elastin. The healing process begins almost immediately after treatment, penetrating deep into the dermal layers and helping repair wrinkles, acne scars, and burn scars. Recently, during hair transplantation, JanuLET has been used topically to reduce the amount of injectable lidocaine and increase patient comfort. As a result, the side effects associated with injectable anesthetics are minimized.

Key Points

Side Effects

The use of local anesthetics usually causes minor issues such as inflammation and skin discoloration at the application site. Repeated use, especially on damaged skin, may interfere with the natural healing process. In rare cases, high doses of the drug may be rapidly absorbed and lead to reactions such as seizures or increased heart rate.

Safety Precautions

Since sufficient studies on the use of this medication during pregnancy have not been conducted, and due to its secretion into breast milk, it should be used with caution and under the supervision of a specialist during pregnancy and breastfeeding.
It should not be used in children under two years of age.
Patients with a history of arrhythmia or those taking cardiac medications should inform their physician.
So far, no reports of toxicity or severe adverse effects related to JanuLET ingredients have been recorded. However, it is recommended not to apply the product on mucous membranes.

Local anesthetics generally cause minor side effects such as inflammation and skin discoloration at the application site. Mild skin reactions such as rash, burning, itching, or irritation may also occur. Repeated application on wounds may interfere with the natural healing process.
In rare cases, high doses of the drug may be absorbed rapidly and cause reactions such as seizures or an increased heart rate.

Store the medication in a refrigerator at 2–8°C and protect it from freezing. Do not use the solution if it has changed color. After each use, tightly close the container cap.

janulet Directions

JanuLET solution should be applied to the area requiring anesthesia during procedures such as micropigmentation, tattooing, hair transplantation, microneedling, diagnostic nasal endoscopy, and similar treatments.

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FAQ

  • Can I inject JanuLET?
    • No. Any intramuscular, intravenous, or intradermal injection of JanuLET is strictly prohibited. This medication is intended for topical use only.
  • I noticed that the color of JanuLET solution has changed. Can I still use it?
    • No. Any color change to dark yellow or brown indicates degradation of the medication, and it must be discarded immediately.
  • How stable is JanuLET at room temperature?
    • It is recommended to store JanuLET in a refrigerator at 2–8°C and protect it from sunlight and freezing. Storage at room temperature (below 25°C) for a short period (for example, up to two days) does not cause any problem. However, monitor the color of the solution — any discoloration indicates instability.
  • How long is JanuLET usable after opening the container?
    • It should be used within one month after opening and must be stored in the refrigerator.
  • What should I do if the medication comes into contact with the eyes?
    • Contact with the eyes may cause mild irritation. Do not rub the eyes. Immediately rinse them with plenty of water for at least 15 minutes. During rinsing, open and close the eyes several times to ensure thorough washing. If symptoms worsen, seek medical attention.
  • What should I do if the medication is accidentally swallowed?
    • If the patient has swallowed the medication, give plenty of water or milk immediately to dilute the active ingredients, then go to the hospital at once. Do not induce vomiting under any circumstances.
  • What if JanuLET was accidentally stored in the freezer?
    • Unfortunately, freezing damages the formulation and destroys its effectiveness. Do not use the medication after thawing.